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formal analysis and investigation, D.M., I.P.H

doi: 10.1186/s12929-018-0493-6 183 TsinariA.RoumeliotisS.NeofytouI

These data reveal that cagrilintide has an amylin-like binding mode but, compared to other peptides, induces distinct conformational dynamics at calcitonin-family receptors that could contribute to its clinical efficacy

The evidence considered here suggests sleep deprivation is associated with several changes to the epigenome, particularly with regard to DNA methylation, histone modifications, and non-coding RNAs (Figure 1)