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-Glu-Ser-Gly treatment significantly decreased levels of nucleotides and nucleotide derivatives (Supplementary Fig

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Zhang H, Liu J, Yao J, He F, Ying X (2024) Two novel ketone alkaloids from Portulaca oleracea L

Interestingly, cancer-associated fibroblasts (CAFs) also display heightened macropinocytosis induced by glutamine starvation or oncogenic signaling, providing a source of intracellular amino acids and secreted amino acids that support CAF functions and tumor cell survival [45,46]

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This high level of H 2 O 2 is also due to the fact that the ER membrane is rather impermeable for H 2 O 2 (Konno et al