glutathione ethanol metabolism Oxidative Biomarkers of Alcohol. MDA, HNE, GSH/ GSSG and acetaldehyde Adaptations in glutathione-based redox protein

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Protein glutathionylation is a major redox-sensitive PTM that can control the activity and stability of target proteins in response to cellular stress, including oxidative stress 135

demonstrated that rats with DPN induced by HG exhibited reduced Beclin-1 and LC3-II/LC3-I ratios in SCs

Reactive oxygen species (ROS) belong to subcellular messengers in signal transductions pathways [21]

Nature 451 , 345349 (2008)

Glutathione binds to tyrosinase, making it less effective thereby slowing down melanin production