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Cellular stress, often observed in the autistic brain [158], activates p53, which inhibits the activity of mTORC1 via AMPK and TSC2 activation [303]

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Synaptic dysfunction in neurodevelopmental disorders associated with autism and intellectual disabilities
Gysin R, Kraftsik R, Sandell J, Bovet P, Chappuis C, Conus P et al (2007)