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During this process, one of the important molecules, HSP70, can bind to Toll-like receptors 4 (TLR4), a type of receptor located on the cell membrane surface, to trigger an inflammatory response and stimulate the body to secrete and synthesize pro-inflammatory cytokines such as TNF- and IL-6, ultimately activating the NF-B pathway and further amplifying the inflammatory response [79]

Rama Rao and Norenberg, 2004

However, the antibody did not recognize protein in extracts from the mouse N2A neuroblastoma cell line, and reacted with additional bands in mouse cortex protein

Oral B12 might need several weeks to boost blood levels