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99 Interestingly, targeting the MCFU with the inhibitor minocycline was effective in protecting against APAP-induced liver injury in vivo

Studies have shown that crocin can improve the histopathological changes caused by doxorubicin (Razmaraii et al., 2016), and attenuated the cardiotoxicity induced by diazinon (Razavi et al., 2013)

Apolipoprotein A-II Experiments in transgenic mice have demonstrated that human apoA-II-enriched HDL served to protect VLDL from oxidation more efficiently than HDL from control animals

When cocultured with PB mononuclear cells, these MenSCs presented increased expression of indoleamine 2,3-dioxygenase-1 and COX-2, as well as elevated secretion of proinflammatory cytokines such as IFN-, IL-10, and monocyte chemoattractant protein-1, suggesting that MenSCs may contribute to disease progression through immunomodulation and altered cellular behavior (Nikoo et al., 2014)