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Furthermore, while the positive study of Simon et al

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Negative control wells contained media with 2 M lapatinib but no additional chemical inhibitors

Chondrogenic maturation To mimic the in vivo differentiation of growth plate chondrocytes in vitro, confluent monolayers were switched to chondrogenic differentiation medium (growth medium supplemented with 50 g ml 1 l-ascorbic acid (Sigma-Aldrich), 10 ng ml 1 recombinant human transforming growth factor-1 (rhTGF-1

The analyst software (Sciex, version 1.7) was used to operate the mass spectrometer and for data processing