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Daily supplementation prevents 100% of bariatric B12 deficiency

PMID 36130677

Other combinations might pair a GLP-1 agonist for appetite control with a growth hormone secretagogue for muscle preservation

In the primary turnover cycle of the MS reaction homocysteine reacts with the methyl group of methionine synthase-bound methylcobalamin to produce methionine and an unstable intermediate form, cob(I)alamin

Marques-Mourlet et al
