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Stepicheva NA, Weiss J, Shang P, et al

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In IDH2-deficient T cells, fatty acids are utilized to sustain the oxidative TCA cycle, leading to enhanced stemness, marked by increased TCF1 expression and cytokine secretion

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RT-PCR Total cell RNA extraction was performed using TRIzol (Invitrogen) and reverse transcribed according to the manufacturers protocol (Takara)