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Figure10 shows the time-line of decline and recovery of hepatic GSH after a therapeutic dose (1 g), and after 5 g, 10 g, 15 g, and 20 g doses, respectively

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Within the United States, probiotic regulation falls under the authority of the FDA, which generally classifies these products as dietary supplements or food ingredients in accordance with the Dietary Supplement Health and Education Act (DSHEA) of 1994 (566)

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A peptide that survives the stomach intact still faces intestinal brush-border peptidases and first-pass hepatic metabolism before it can reach systemic circulation