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Folate deficiency in pregnancy is associated with preventable and serious fetal harm, i.e., neural tube defects (NTD)

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Proton pump inhibitors and similar medications that lower stomach acid might decrease the absorption of vitamin B12 from food, but this is less of a concern when receiving B12 injections because they bypass the digestive system entirely

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It was confirmed that NNMT knockdown contributes to significant suppression of cell proliferation and anchorage-independent cell growth in vitro and in vivo (61)