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Due to the failure of anti-ICAM-1 in human trials, a blinded placebo-controlled trial of non-human primate stroke significantly improved the neurological function of treated animals and significantly reduced the infarct size by using huep5c7 (human monoclonal antibody against e-selectin and p-selectin), which provided a new possibility for the treatment strategy of anti-inflammatory response by blocking adhesion molecules and leukocyte infiltration (Mocco et al., 2002)

Zhao Y, Li Q, Zhu T, He J, Xue P, Zheng W, Yao Y, Qu W, Zhou Z, Lu R, Zhou Z, He R, He M, Zhang Y (2021a) Lead in synergism with IFN acts on bone marrow-resident macrophages to increase the quiescence of hematopoietic stem cells

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This general sense of puling wimpiness pervades the palate as well

Conversely, attenuation of fibrotic scarring enhances axonal regeneration and improves sensorimotor function recovery 176