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It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca 2+ ions

Applying an ice pack on the injected areas for around 10-20 minutes after the injection would soothe you big time

Pickart stated that GHK-Cu has a favorable safety profile, highlighting that there is no indication that it causes side effects in test subjects [2]: The molecule is very safe and no issues have ever arisen during its use as a skin cosmetic or in human wound healing studies. In a 2018 review based on new genetic data, he reiterated that all biological actions associated with GHK appear to be health positive. He pointed to over four decades of GHK research encompassing cell, tissue, and animal studies, also noting the peptides inclusion in commercial anti-aging and cosmetic products such as creams, liposomes, and dermal patches [1]

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Start with low concentrations: If you are new to using facial antioxidants, begin with lower strengths and gradually increase as your skin builds tolerance