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Individuals with severe liver disease (such as cirrhosis or hepatic encephalopathy) or severe kidney disease should not take L-Glutamine, as their organs may be unable to effectively clear the resulting ammonia, leading to dangerous neurotoxicity

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Cardinale A., Calabrese V., de Iure A., et al., AlphaSynuclein as a Prominent Actor in the Inflammatory Synaptopathy of Parkinson's Disease, International Journal of Molecular Sciences 22, no
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