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Study selection Two of the authors (IP, MP) performed the eligibility assessment in an independent, unblinded and standardised manner

PMID 17380034

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Oxygen solubility factors relative to pure water were set to 0.92, and stirrer speed to 200

In animal models, resveratrol treatment, at a dose roughly equivalent to 56 mg for an adult human, has been shown to inhibit renal oxidative stress, improve kidney circulation, and increase survival in sepsis-related acute kidney injury (Holthoff 2012)

The MOTS-c peptide , encoded in mitochondrial DNA, has therefore been investigated as a potential tool for extending healthspan and delaying age-related decline