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By suppressing NF-B activation, silymarin reduces the production of inflammatory cytokines and chemokines, thereby mitigating liver inflammation and preventing further cellular injury

That body of evidence is bigger not because retinol works better across all endpoints, but because research funding has historically concentrated there

Association of methylphenidate-induced craving with changes in right striato-orbitofrontal metabolism in cocaine abusers: implications in addiction

Nov 8 2003;362(9395):1527-35

EC 2.5.1.1.8) are key phase II detoxification enzymes that work downstream of Cyt P450s in cellular metabolism

doi: 10.1016/j.arr.2022.101619 99