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The CDOCKER algorithm was used to dock the ligands, allowing for the generation of ten random ligand conformations, while the heating target temperature was set to 700 K and full potential mode was employed

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[4,5] Glutathione is found to be most concentrated, respectively, in the liver, spleen, kidneys, eye lenses, erythrocytes, and leukocytes

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Because SAM is required for hundreds of methylation reactions, including those that build creatine and glutathione, low levels of SAM can ripple across nearly every body system

found that another amino acid transporter, SLC25A22, could promote Asp synthesis, activate the AMPK pathway and reduce oxidative stress in KRAS mutant colorectal cancer (CRC) cells (Fig