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Contraindications and Carcinogenicity Pramlintide is contraindicated in patients with gastrointestinal diseases and those undergoing therapy with alpha-glucosidase inhibitors due to the increased risk of nausea [57]

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The second receptor is GIP

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Interestingly, genetic deficiency of ICAM-1 and/or MCP-1 protects against diabetic nephropathy by reducing the number of renal macrophages (57)

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