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In comparison with DFO, patients treated with DFP exhibit more pronounced improvement in cardiac T2* values (123), higher left ventricular ejection fraction (123, 124), stronger cardiac protective effects (125), and a higher 5-year survival rate without heart disease (122)

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Our analysis of whole retinal lysate yielded no changes in BNIP3, BNIP3 dimer, or NIX protein levels (Figures 8A,B,F)

PLC pathway increases intracellular calcium affecting various cellular processes
