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Recent investigations have shown that trigonelline, a compound extracted from the plant fenugreek, can obstruct FMO3, thereby preventing the conversion of TMA to TMAO (87)

and intervention duration (short-term studies 12 weeks showed greater LDL-C and HDL-C changes, possibly reflecting acute metabolic shifts that stabilize over time)

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Available online: [PubMed] [Google Scholar] 47.Giamberardino M.A., Dragani L., Valente R., Di Lisa F., Saggin R., Vecchiet L

J Alzheimers Dis (2022) 87(4):167181