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Among DNMTs, the de novo methyltransferases DNMT3A and DNMT3B establish methylation patterns on unmethylated DNA through embryonic development (Figure 1) (Smallwood et al., 2011)

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Here, we provide an updated perspective on the renaissance of the field and discuss how the integration of synthetic biology and artificial intelligence (AI) is overcoming these historical barriers, including AI-driven tools such as Cello and SHASI-ML

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Moreover, Treg cells can restrict CD4 + T cell overactivation and its dysfunction is involved in SLE pathogenesis (5961)

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Conjugation technology is another important aspect of ADCs, by which payloads and linkers are covalently attached to the antibodies

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What endpoint markers should be measured to verify that stacking MOTS-c 5-Amino-1MQ is producing the expected metabolic effects

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