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doi: 10.4049/jimmunol.150.11.4733 44 WoltersPJRaymondWWBlountJLCaugheyGH

In type 2 diabetic patients, co-treatment with rhIGF-I can significantly reduce glucose levels and insulin requirement[305] while improving glucose tolerance, hyperinsulinemia, and hypertriglyceridemia[306]

From plants to psycho-neurology: unravelling the therapeutic benefits of bioactive compounds in brain disorders

Caution is advised regarding the use of oral supplements in patients with pernicious anaemia, meaning that careful monitoring of symptoms would be required, and is not generally advised in patients with neurological symptoms, owing to limited efficacy and potentially serious impact of permanent neurological damage[25]

2 Department of Protozoology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan

Effects of ketogenic diet on muscle metabolism in health and disease
