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Riboflavin deficiency may be associated with an increased risk of anemia during pregnancy, and RCTs conducted in pregnant populations have demonstrated that the inclusion of riboflavin with other micronutrient supplements (namely iron and folic acid) leads to greater improvements in hematological parameters, such as hemoglobin concentration, RBC count, and anemia prevalence (reviewed in 62)

Nausea, abdominal discomfort, or gastroesophageal refluxall documented with tirzepatidecan interfere with sleep onset and maintenance

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Furthermore, iron serves as cofactor for numerous enzymes, including catalase and peroxidases involved in antioxidant defense, cytochrome P450 enzymes that mediate drug metabolism, and hydroxylases essential for the synthesis of neurotransmitters

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