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It was also reported to cause a vasorelaxant effect in rat aortic rings, though the mechanism for this relaxation was not determined (Amrani et al., 2)

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Ferroptosis inducers (FINs) are currently classified based on various mechanisms, including those targeting the Xc system, GPX4 inhibitors or degraders, compounds that deplete coenzyme Q10, and lipid peroxidation inducers (for details, refer to the review by JIN X) ( -inhibitors effectively induce ferroptosis in tumor cells by blocking cystine uptake, depleting GSH, and promoting lipid peroxidation

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These replicative processes imply a highest rate of mitochondrial oxygen consumption and reactive oxygen species (ROS) generation

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