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Luteolin can also increase the expression of antioxidant enzymes such as heme oxygenase-1 (HO-1) via the nuclear factor erythroid 2related factor 2/ antioxidant responsive element (Nrf-2/ARE) complex activation, as it was observed in in vitro models of PD [44, 57] and H 2 O 2 -induced toxicity in in vitro models [5860]
10.1007/s10541-005-0104-5 Biochemistry ( Mosc
[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Getahun D, Nash R, Flanders WD, et al
European Journal of Clinical Investigation
Oxidative stress in cancer: From tumor and microenvironment remodeling to therapeutic frontiers
