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Some studies suggest that CSCs rely preferentially on glycolysis, accompanied by low OXPHOS and high lactate production, while others point to OXPHOS as their main energy source [216, 217]
As a result, catastrophic NAD + depletion evokes metabolic collapse and axonal degeneration [76,77,78,79]

Bykov VJ, et al

However, we did not detect any changes in the transcription of glt-1 after treatment with BSO (data not shown), suggesting that xct upregulation could lead to increased extracellular glutamate levels, as observed in mice that have been gestationally exposed to arsenic (Ramos-Chvez et al., 2015

Na + will constantly leak into the cell, as its equilibrium potential (+60 mV) is more positive than the resting membrane potential of -70 mV

Performing as a four-piece, however, the resulting chemistry turned Grizzly Bear into a band of equal collaborators, with Rossen becoming its co-lead vocalist and second principal songwriter and Taylor adopting the role of producer and multi-instrumentalist
