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High-risk patients including those on long-term or high-dose metformin, older adults, and those with additional risk factors should be considered for periodic B12 monitoring

Vitamin B12, also known as cobalamin, is a water-soluble vitamin essential for red blood cell production, DNA synthesis, and neurological function

doi: 10.1016/s0928-4257(01)00040-7

What does not change regardless of which compound a lab chooses is that it still requires reliable, high-quality substance that has been properly tested to ensure its purity

Protocols, doses, and reactions reported below come from published research and self-reported community sources

doi: 10.1002/14651858.CD006612.pub5