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Active CASP8 cleaves BH3 interacting domain death agonist (BID) to generate truncated BID (tBID), thereby linking death receptor signaling to the mitochondrial pathway through BAX- and BAK1-mediated MOMP
doi:10.1073/pnas.0908786106 Iwasaki S, Yamasoba T
As shown in Figure 7B, the interactions among the pathways mainly relate to amino acid and carbohydrate metabolism
