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Chemistry of pyridoxine in drug design
A potential site of therapeutic intervention could be at the level of the host enzyme machinery necessary for the conversion of TMA to TMAO
org/10.1097/PSY.0000000000000537 Virmani, M
Specifically, regulation of phosphoenolpyruvate carboxykinase (PEPCK), the rate-limiting step in gluconeogenesis, is critical for glucose homeostasis and has been shown to be regulated by TR and CCAAT enhancer-binding protein in the liver (193)
doi: 10.1001/archneur.61.1.82 229
10.3390/ijms25042370 Int J Mol Sci
