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Another potential mechanism of action for the pain-reducing properties of vitamin B12 comes from interactions with prostaglandin synthesis, including cyclooxygenase (COX) enzymes

A Few Notes On Giving Yourself Vitamin B12 Shots Once your doctor prescribes B12, I recommend asking for insulin-size needles

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GS2 lipase activity has subsequently been confirmed in keratinocytes (35) and in 293 HEK cells overexpressing the enzyme (62)

Instead, it works by supporting tissue repair, reducing inflammation, and promoting healing in areas like muscles, tendons, and ligaments

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