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The oncometabolites are produced by mutations in the nuclear-encoded TCA enzymes, isocitrate dehydrogenase 1 and 2 (IDH1/2), succinate dehydrogenase (SDH), and fumarate hydratase (FH) (177)

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Amino Acid Transport GSH is also involved in the transport of amino acids across cell membranes, supporting protein synthesis and repair processes

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