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308 When PBIT was used, the cell survival rate of cisplatin-resistant canine melanoma cell line decreased, indicating that inhibiting KDM5B can reduce the resistance of cells to cisplatin (Fig

L-Carnitine plays a role in helping transport fatty acids into cells, where they can be used as part of the energy-producing processes

Nat Rev Mol Cell Biol 22:266282

PMID: 34335481

ICI-induced liver injury is depend on: 1-Type of molecule: CTLA-4 or PD-1/PD-L1, 2-ICI-dose level : In cases treated by ipilimumab, the rates of grade III-IV irAEs are seen in 0%, 7% and 25% of the cases treated with 0.3mg/kg, 3mg/kg and 10mg/kg

Therefore, the triplet with bevacizumab did not improve patient outcome compared to chemotherapy alone after induction chemotherapy