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Survival of the fittest: Cancer stem cells in therapeutic resistance and angiogenesis

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Akterin S, Cowburn RF, Miranda-Vizuete A, Jimenez A, Bogdanovic N, Winblad B et al

Se exhibits a dual effect, as nucleophile and electrophile, and showed better redox properties than sulfur

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Multiple in vitro studies showed that when endothelial cells are exposed to various stimuli mimicking metabolic changes leading to endothelial dysfunction, such as native LDL and Ox-LDL [79], angiostatin [80], homocysteine [81], and high glucose [82,83], they become increasingly vulnerable to eNOS uncoupling