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It would therefore be reassuring to verify these computational models by crystallographic studies

However, any clinical application remains premature and contingent on replication in larger, independent cohorts

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Lastly, the International Restless Leg Syndrome Study Group rating scale (IRLSS) appraises the presence and severity of RLS and is a valuable tool specifically in patients with primary biliary cholangitis (31, 33, 36)

Various dietary interventions including GFCF diet, GAPS, FODMAP diet, ketogenic diet, Mediterranean diet, Feingold, Candida body ecology, allergy elimination diets, specific carbohydrate diet, etc.) and supplements (vitamin D, polyunsaturated fatty acids, probiotics and prebiotics, phytochemicals) are used to alleviate these symptoms

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