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Cellular Therapy, using autologous or ethically sourced allogeneic stem cells, holds immense potential to modulate hyperactive immune responses, promote vascular repair, and restore damaged connective tissue across various organs

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Healthier mitochondria enhance gamete viability and developmental outcomes

Fujita H, Tanaka YK, Ogata S, Suzuki N, Kuno S, Barayeu U, et al

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There are two 2HG enantiomers: D-2-hydroxyglutarate (D2HG) and L-2-hydroxyglutarate (L2HG), with the former predominantly generated from IDH1 mutants and PHGDH while L2HG is primarily generated from the promiscuous activity of LDHA and MDH1/2 under hypoxic or acidic conditions and converted back to 2OG by L2HGDH