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However, if split dosing improves your adherence and reduces side effects, the practical benefit may outweigh theoretical pharmacokinetic concerns

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Lei H, Peng X, Ouyang J, Zhao D, Jiao H, Shu H, Ge X (2015) Protective immunity against influenza H5N1 virus challenge in chickens by oral administration of recombinant Lactococcus lactis expressing neuraminidase

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