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Whole root granules of 12,000 mg/day (equivalent to 6,000 mg of root powder) have also been used (ODS 2023)

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Reinstatler L, Qi YP, Williamson RS, Garn JV, Oakley GP Jr (2012) Association of biochemical B deficiency with metformin therapy and vitamin B supplements: the National Health and Nutrition Examination Survey, 19992006

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Your CHC medical provider will determine which option is best for you based on your medical history