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Most others who Ive spoken with that had more severe acute reactions like nausea etc
What does the Cys7-Cys14 disulfide bond do for the molecule

F., Onishi, K., Buford, D., Peng, J., Mahmood, A., et al

In the chronic toxicity experiment, L-NAME caused severe tissue damage (myocardial and hepatic cell necrosis, necrosis of the lymphoid cells in the spleen) while L-arginine provoked predominantly congestion, edema and hemorrhages in all organs

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