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Invited Articles Borthakur G
V.PassosL
Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice
Dissel, S
Metabolic intermediates for biosynthesis Despite the original idea of Warburg [2] that aerobic glycolysis was originated as a consequence of mitochondrial dysfunction, subsequent studies showed that mitochondria of cancer cells are still functional and able to conduct oxidative phosphorylation
Specifically, the GPX4 inhibitors RSL3 and ML210 were identified to selectively kill melanoma persisters derived with BRAFi and MEKi treatments 12
