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Furthermore, current potential therapeutic strategies targeting inflammatory pathways are reviewed, including anti-inflammatory agents (e.g., cyclooxygenase-2 (COX-2) and NLRP3 inhibitors), antioxidants (such as N-acetylcysteine (NAC) and melatonin), probiotic modulation (via gut-brain axis (GBA) regulation), and precision therapies (such as mesenchymal stem cells (MSCs) and exosome-based approaches)
Arch Dermatol 1998

So the protective effect of -glutathione might be due to an ability to block oxidative stress

GSH Favourable Effects on Cancer Cells While being an interesting weapon against chemotherapy-induced toxicities, it is mandatory to assess that GSH, as an anti-oxidative agent, might have a potential protective role on cancer cells, reducing anticancer treatment efficacy