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A tracheostomy may be the last resort if all other treatment options are ineffective, particularly in morbidly obese patients who have severe OSA, severe oxygen desaturation, and/or concomitant cardiac disease (Qureshi, 2003)

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ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism

Table III

However, AT-EVs cannot be strictly termed as ADSC-EVs, since the adipose tissue is composed of multiple cell types including ADSCs and others such as mature adipocytes and macrophages

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