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Description
The role of nuclear hormone receptors in cannabinoid function

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From a physiological standpoint, LCR serves as a substrate for the enzyme carnitine palmitoyltransferase as well as the synthesis of acetylcarnitine, which is necessary for maintaining a feasible pool of free coenzyme A (CoA), allowing for continuation of pyruvate dehydrogenase complex (PDC) and tricarboxylic acid cycle flux 2

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This bidirectional regulatory effect disrupts immune homeostasis and promotes the cascade amplification of inflammatory responses
