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Last month, the Centers for Disease Control and Prevention updated its guidance to say that the second shot should be administered within the prescribed time frames where possible, but that the second dose of the Moderna and the Pfizer-BioNTech vaccines could be delayed up to six weeks, if necessary

Step 5: Analytical Quantification (HPLC/UV/Fluorescence) The concentration of the drug in the free and/or encapsulated fractions is quantified using the chosen analytical technique

It's a risk that isn't worth taking
At the moment, the most accurate answer is that safety has not been fully established in humans
