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John's wort extract and hyperforin protect rat and human pancreatic islets against cytokine toxicity

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(Photo of tummy and thigh panniculitis) Kaur, H, C Reyes-Barron, WH Sipprell, A Cameron, T Louie, PR Tsai, and G Scott, 2022

Note the pigmented nail band and extension of pigmentation to proximal nailfold

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This mechanism of action is responsible for the reduction of the lipid deposits in the blood vessels, which may diminish the risk of atherosclerosis
