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doi: 10.3390/ijms24044039

Sermorelin was approved for treating growth hormone deficiency in children, though the manufacturer pulled it from the market in 2008 for commercialnot safetyreasons

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The functional differences in CLPX regulation between yeast and vertebrate ALAS are likely due to primary sequence differences as regions that are important for the interaction between yeast CLPX and ALAS are not conserved in the vertebrate ALAS proteins (Rondelli et al., 2021)