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In detail, increased pro-oxidative status, including impaired antioxidant defense, abnormal serum, plasma, and red blood cell (RBC) oxidative stress parameters, development of redox dysregulation, impaired docosahexaenoic acid levels, and impaired glutathione synthesis have been reported in meta-analytic studies across stages and the broad diagnostic spectrum of psychosis with evidence of independency concerning antipsychotic medication

PMID: 18936223

Autophagy modulation as a potential therapeutic target for diverse diseases

doi: 10.3382/ps.2013-03827

Mechanism two (homocysteine NMDA excitotoxicity) : low mood, vascular dementia, memory issues, nervous system disease, stroke risk, and multiple sclerosis