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SI has the ability to modulate pro-inflammatory cytokines TNF- and IL-6 in diabetic rats, ameliorating inflammation and impacting diabetic conditions positively (Rojanaverawong et al., 2023)

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DeHart DN, Fang D, Heslop K, Li L, Lemasters JJ, Maldonado EN (2018) Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells

A 2011 trial showed that 50 mg/kg/day of MSM reduced markers of oxidative stress in athletes after exhaustive exercise suggesting MSM plays a role in buffering the damage of intense training (Nakhostin-Roohi et al., 2011)