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Under aerobic condition, the participation of oxygen in redox reactions is unavoidable and a variety of highly reactive chemical entities are produced

doi: 10.3389/fphar.2022.1040857 Received 09 September 2022 Accepted 02 November 2022 Published 24 November 2022 Volume 13 - 2022 Edited by Yasmina Mohammed Abd EL-Hakim, Zagazig University, Egypt Reviewed by Ali Hafez El-Far, Damanhour University, Egypt Ehab Yahya Abdelhiee, Matrouh University, Egypt Updates Copyright 2022 Algaidi, Faddladdeen, Alrefaei, Qahl, Albadawi, ALmohaimeed and Ayuob

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Ghanizadeh A, Derakhshan N, Berk M

Also, there are factors such as differences in the nasal anatomy and physiology of animal species and humans, making it difficult to obtain a direct correlation between them when translating preclinical findings to clinical research

Lesions in the mtDNA are known to contribute to tissue damage, age-related decline, and to disease
