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For example, ROS drive hypoxia-inducible factor 1 (HIF1) mediated GLUT1 expression, hexokinase activity, and resultant glycolysis in response to low oxygen tension as part of the angiogenic response (27) The co-localization of neutrophil phosphofructokinase 2 with NOX2 leads to its activation, resulting in NADP+ production as its byproduct, facilitating an enhanced glycolytic rate

Recent methodological improvements have addressed these limitations through the development of a modified DTNB protocol that eliminates the need for protein precipitation while maintaining analytical accuracy [17]

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243 developed folate-targeted dendrimers that are able to load and release L-BSO, whereas Santos et al