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BioMed research international, 2019, 8086257

Therefore, in this review, we aim to discuss the role of GPCRs in the pathogenesis of AKI and summarize the relevant clinical trials involving GPCRs to assess the potential of GPCRs and their ligands as therapeutic targets in AKI and the transition to AKI-CKD

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Peripheral receptors in uterine and mammary tissues mediate well-known obstetric effects, but intranasal administration targets predominantly central actions, minimizing uterotonic activity at therapeutic psychiatric doses